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Continuous Glucose Monitors: New Developments in CGM Technology

Article written and reviewed by Cyrus Khambatta, PhD
Published July 25, 2017
Continuous Glucose Monitors

Checking your blood glucose can be a tiresome (but necessary) part of living with diabetes.

Testing your blood glucose using a glucometer gives you snapshots of your blood glucose profile at isolated times during the day. Continuous glucose monitors, on the other hand, allow you to see what your blood glucose is doing throughout the day, by taking measurements approximately every 5 minutes.

In the next few years, everyone will be able to use continuous glucose monitors to track their blood glucose. Athletes, professionals, coaches, people living with prediabetes and type 2 diabetes, coaches and medical professionals will soon have CGM technology at their fingertips.

I wrote an article about this for KQED a few years ago, so read it to gain more appreciation for the importance of CGM technology for non-diabetic individuals.

This is great news, because tracking your blood glucose is a powerful way to gain insight into how your food, exercise and stress affect you in ways that were previously invisible. 

There are a number of companies currently developing technology to continuously measure blood glucose non-invasively. Some of the best known companies are summarized below:

Verily

Verily (Google's life science team) and Dexcom have teamed up to develop a miniature continuous glucose monitor (CGM) to help people with type 2 diabetes measure blood glucose continuously. Dexcom manufactures CGMs for people with type 1 diabetes, however they are generally not available to patients with prediabetes or type 2 diabetes.

This partnership is focused on minimizing both the cost and the size of the components. And it goes without saying that these sensors would be fully cloud-compatible, for all tech nerds to enjoy.

Sano

Sano has developed a biometric sensor in a low-profile patch that is designed to measure your blood glucose and relay that information to your mobile phone. The patch measures interstitial fluid in your skin’s top layer to provide real-time, continuous glucose monitoring.

Google

Google is actively developing a contact lens with embedded microchips and miniaturized electronics that would measure glucose in your eye fluid, and wirelessly send the data to your mobile device.

This technology eliminates the need to wear a patch on your skin, and instead utilizes sophisticated technology in a contact lens which eliminates the need for blood from a finger stick.

Who knew that your tears had such valuable information?

Apple

Apple is apparently working on a "top secret" project, led by a group of biomedical engineers. Some believe that they are developing optical sensors which can detect glucose by shining light through your skin.

It is hard to get any information about Apple's CGM technology, so perhaps we'll just expect them to release another device with space age technology, as always.

Helo

The World Global Network developed a wristband, called Helo, that can be worn 24-7 and is a real-time health monitoring device that measures your vitals.

In addition to your blood glucose, the Helo device measures your emotions, fatigue, sleep quality, exercise, blood pressure, heart rate and ECG, and is capable of wirelessly alerting a family member or friend about a health emergency.

GlucoWise

The company GlucoWise is developing a sensor that gently squeezes either the skin between your thumb and pointer, or the skin on your earlobe.

The device then wirelessly relays your blood glucose value to your mobile device, and stores all your data in the cloud. According to the company, "It will take no more than 10 seconds to provide a simple, fast and highly discrete testing experience."

GlucoTrack

GlucoTrack has developed a device that is approved in Italy and Spain; it is not approved in the United Kingdom, France, Germany or the United States.

The device is bulky and slightly cumbersome, and measures blood glucose using a device that clips to your ear. Clip the device to your ear, sit back and wait as it measures your blood glucose non-invasively.

In addition, the device provides you with an estimated A1c value, helpful for giving an indication of your 3-month blood glucose average.

Alertgy

The Alertgy CGM is a band that you wear on your wrist that monitors your blood glucose and wirelessly transmits the result to your smartphone.

The band is waterproof, hypoallergenic, and can be worn 24 hours a day. The company claims that the device will be available in 2020, and they are currently in the prototyping phase.

The wristband leverages technology developed for military application.

Enter to Win 1 Year of Free Access to the Nutrino Mobile App ($79 Value)

Share this article on social media and leave a comment below, and you will be entered in a drawing to receive 1 year of access to Nutrino Premium, valued at $79. 

We have partnered with Nutrino, a mobile app technology that allows you to learn how your food affects your blood glucose.

We interviewed the Chief Scientific Officer Yaron Hadad in the Mastering Diabetes Online Summit back in February 2017, and he explained how their app uses machine learning algorithms to understand how individual foods affect your blood glucose. When I saw their technology, I was BLOWN away. 

Their app is also extremely useful for finding plant-friendly places to eat, for discovering plant-friendly recipes and for logging your food intake effortlessly. 

Share this article on social media and leave a comment below, and you will be entered in a drawing to receive 1 year of access to Nutrino Premium, valued at $40. 

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About the author 

Cyrus Khambatta, PhD

Cyrus Khambatta, PhD is a New York Times bestselling co-author of Mastering Diabetes: The Revolutionary Method to Reverse Insulin Resistance Permanently in Type 1, Type 1.5, Type 2, Prediabetes, and Gestational Diabetes.

He is the co-founder of Mastering Diabetes and Amla Green, and is an internationally recognized nutrition and fitness coach who has been living with type 1 diabetes since 2002. He co-created the Mastering Diabetes Method to reverse insulin resistance in all forms of diabetes, and has helped more than 10,000 people improve their metabolic health using low-fat, plant-based, whole-food nutrition, intermittent fasting, and exercise.

Cyrus earned a Bachelor of Science in Mechanical Engineering from Stanford University in 2003, then earned a PhD in Nutritional Biochemistry from the University of California at Berkeley in 2012. He is the co-author of many peer-reviewed scientific publications.

He is the co-host of the annual Mastering Diabetes Online Summit, a featured speaker at the Plant-Based Nutrition and Healthcare Conference (PBNHC), the American College of Lifestyle Medicine Conference (ACLM), Plant Stock, the Torrance Memorial Medical Center, and has been featured on The Doctors, NPR, KQED, Forks Over Knives, Healthline, Fast Company, Diet Fiction, and the wildly popular podcasts the Rich Roll Podcast, Plant Proof, MindBodyGreen, and Nutrition Rounds.

Scientific Publications:

Sarver, Jordan, Cyrus Khambatta, Robby Barbaro, Bhakti Chavan, and David Drozek. “Retrospective Evaluation of an Online Diabetes Health Coaching Program: A Pilot Study.” American Journal of Lifestyle Medicine, October 15, 2019, 1559827619879106. https://doi.org/10.1177/1559827619879106

Shrivastav, Maneesh, William Gibson, Rajendra Shrivastav, Katie Elzea, Cyrus Khambatta, Rohan Sonawane, Joseph A. Sierra, and Robert Vigersky. “Type 2 Diabetes Management in Primary Care: The Role of Retrospective, Professional Continuous Glucose Monitoring.” Diabetes Spectrum: A Publication of the American Diabetes Association 31, no. 3 (August 2018): 279–87. https://doi.org/10.2337/ds17-0024

Thompson, Airlia C. S., Matthew D. Bruss, John C. Price, Cyrus F. Khambatta, William E. Holmes, Marc Colangelo, Marcy Dalidd, et al. “Reduced in Vivo Hepatic Proteome Replacement Rates but Not Cell Proliferation Rates Predict Maximum Lifespan Extension in Mice.” Aging Cell 15, no. 1 (February 2016): 118–27. https://doi.org/10.1111/acel.12414

Roohk, Donald J., Smita Mascharak, Cyrus Khambatta, Ho Leung, Marc Hellerstein, and Charles Harris. “Dexamethasone-Mediated Changes in Adipose Triacylglycerol Metabolism Are Exaggerated, Not Diminished, in the Absence of a Functional GR Dimerization Domain.” Endocrinology 154, no. 4 (April 2013): 1528–39. https://doi.org/10.1210/en.2011-1047



Price, John C., Cyrus F. Khambatta, Kelvin W. Li, Matthew D. Bruss, Mahalakshmi Shankaran, Marcy Dalidd, Nicholas A. Floreani, et al. “The Effect of Long Term Calorie Restriction on in Vivo Hepatic Proteostatis: A Novel Combination of Dynamic and Quantitative Proteomics.” Molecular & Cellular Proteomics: MCP 11, no. 12 (December 2012): 1801–14.
https://doi.org/10.1074/mcp.M112.021204





Bruss, Matthew D., Airlia C. S. Thompson, Ishita Aggarwal, Cyrus F. Khambatta, and Marc K. Hellerstein. “The Effects of Physiological Adaptations to Calorie Restriction on Global Cell Proliferation Rates.” American Journal of Physiology. Endocrinology and Metabolism 300, no. 4 (April 2011): E735-745. https://doi.org/10.1152/ajpendo.00661.2010




Bruss, Matthew D., Cyrus F. Khambatta, Maxwell A. Ruby, Ishita Aggarwal, and Marc K. Hellerstein. “Calorie Restriction Increases Fatty Acid Synthesis and Whole Body Fat Oxidation Rates.” American Journal of Physiology. Endocrinology and Metabolism 298, no. 1 (January 2010): E108-116.
https://doi.org/10.1152/ajpendo.00524.2009