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Low-Carb Diet vs. Low-Fat Diet – How Jessica Increased Her Insulin Sensitivity 25x in 6 Months by Transitioning to a Low-Fat Diet

Article written and reviewed by Cyrus Khambatta, PhD
Published April 12, 2017

Meet Jessica.

Since the time she was diagnosed with type 1 diabetes in 1996, she has worked hard to follow a strict low-carb diet, in order to control her blood glucose to the best of her ability. Over the course of time however, she found that no matter how few carbohydrate-rich foods she ate, her blood glucose was quite challenging to control.

Low-Carb Diet

Searching for an easier approach to managing diabetes, Jessica adopted a low-carb diet in 2015. On her low-carb diet, she reduced her total carbohydrate intake to approximately 20 grams per day, hoping that it would give her tight blood glucose control.

Following this low-carb diet, Jessica's blood glucose was chronically elevated. Routinely, when she checked her blood glucose - either before or after a meal - she often saw values in the high 200s or low 300s.

Increasing Medication Requirements

To cope with increasing insulin requirements, Jessica’s doctor recommended starting 1000 mg of Metformin on a daily basis in addition to basal and bolus insulin. She found her doctor’s advice quite strange, given that Metformin is often prescribed for people with type 2 diabetes suffering from insulin resistance.

Despite this, she followed her doctor's advice and began taking 1000 mg of Metformin per day, desperate for any solution that would help improve her diabetes health.

Jessica found herself losing energy rapidly. From the time she woke up in the morning to the time she went to sleep, staying awake seemed increasingly difficult, and exercise was almost entirely out of the question.


Jessica knew something was terribly wrong, she just didn't know what to do to improve her health.

Enter Low-Fat, Plant-Based, Whole-Food Nutrition

While perusing on the Internet, Jessica stumbled across our website, and was intrigued by our low-fat, plant-based, whole-food approach to improving insulin sensitivity for people with type 1 diabetes.

She found our evidence-based approach to nutrition intriguing, and decided to enroll in our coaching program for type 1 diabetes.

In the first 3 weeks, Jessica transitioned from a low-carb diet to a low-fat diet, plant-based, whole-food lifestyle, by significantly increasing her intake of fruits and vegetables and reducing her intake of animal products.Initially, she was nervous that eating carbohydrate-rich foods would dramatically increase her insulin use, but despite this she started her program with an open mind, hopeful to experience positive change transitioning away from a low-carb diet.

After only 90 days on her program, Jessica’s carbohydrate intake had increased from approximately 20 grams per day to about 325 grams per day, significantly higher than she thought was possible for a person living with type 1 diabetes.

In that same 30 day period, she found that her blood glucose had become significantly more predictable, and in an effort to avoid hypoglycemia multiple times per day, she stopped using Metformin altogether.

Increased Insulin Sensitivity

Jessica remembers that the most surprising part of the first 3 months of her low-fat journey was how rapidly her basal and bolus insulin requirements fell.

Following a low-carb diet, she averaged 20 units of basal insulin and 17.5 units of bolus insulin per day while eating about 20 grams of carbohydrate. Her baseline 24-hour insulin sensitivity was therefore 0.5 grams/unit.

By the end of the first 3 months, her basal insulin requirements had fallen to 14 units per day and her bolus insulin requirements had fallen to about 15 units per day, even though her carbohydrate intake had significantly increased to 325 grams per day. Her new 24-hour insulin sensitivity was therefore 11.2 grams/unit.

Insulin Sensitivity Equation
Low Carb Diet Insulin Sensitivity 1

She had heard stories from other people in the group coaching program that her insulin sensitivity would likely increase following a low-fat, plant-based, whole-food lifestyle, but it wasn't until she experienced it for herself that she began to understand just how rapidly these changes took place.

Jessica returned to her active lifestyle, performing exercise whenever she wanted. She found that the more she continued to eat low-fat, plant-based, whole-foods, the more energy she gained, and the more weight she lost.

At the 6 month marker, Jessica had lost 15 pounds, and had improved her insulin sensitivity by more than 20x. Her basal insulin requirements had fallen to 11 units per day, and her bolus insulin requirements had fallen to approximately 14 units per day. Now, her 24-hour insulin sensitivity is 13.0 grams/unit.

Low Carb Diet Insulin Sensitivity 2

Whole Body Health

Jessica now feels as though her total body health is completely within her control, and by continuing with a low-fat, plant-based, whole-food lifestyle, she is able to control her blood glucose, body weight, and energy levels simultaneously.

For the first time in her life with diabetes, she feels in full control of her health, and is able to do the things that she loves most: exercise, eat, and be merry.


We are extremely proud of the progress that Jessica has made over the past 6 months, and hope that her story to transition away from a low-carb diet inspires others living with type 1 diabetes about how they can achieve similar results.

If you’re interested in learning more about nutrition and fitness coaching for increasing insulin sensitivity, click here or click on the image below to see if you qualify.

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About the author 

Cyrus Khambatta, PhD

Robby Barbaro, MPH is a New York Times bestselling co-author of Mastering Diabetes: The Revolutionary Method to Reverse Insulin Resistance Permanently in Type 1, Type 1.5, Type 2, Prediabetes, and Gestational Diabetes.


Robby was diagnosed with type 1 diabetes at the age of 12 and has been living this lifestyle since 2006. In that time, while eating pounds of fruit every day, his HbA1c has been stable with a current A1c of 5.3%, TIR of 92%, and average total daily insulin use of 30 units.


Robby graduated from the University of Florida and is the cofounder of Mastering Diabetes and Amla Green. He worked at Forks Over Knives for six years before turning his attention in 2016 to coaching people with diabetes full time.


He is the co-host of the annual Mastering Diabetes Online Summit, a featured speaker at VegFest LA, and has been featured on The Doctors, Forks Over KnivesViceThrive MagazineDiet Fiction, and the wildly popular podcasts the Rich Roll PodcastPlant ProofMindBodyGreen, and Nutrition Rounds.


Robby enjoys exercising every day, spending time with friends, and sharing his lifestyle on Facebook, Twitter and Instagram.

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